So, hello everyone. Today I would like to take this opportunity to discuss some of the interesting subjects in our field and I would like to try to generate some discussion with you all based on the most common questions which I come across during my daily consultations with our patients. One of the most common questions I always get, which I think it is important to address is quality versus quantity of the eggs. The typical question of all I receive from my patients is: “Doctor, how many eggs do I really need to have the maximum chance of getting pregnant?” I also get questions like: “They told me that my ovarian reserve is excellent. Last time, I made 25 eggs but I’m still not getting pregnant. Why?” Or sometimes, I’ll get questions like this: “Doctor, I’m 32 years old and they told me that my AMH is 0.4 and my antral follicle count is less than 3.” In another words, they are told that their ovarian reserve is 60-80% below the average for their age group and they are told that they have a very low chance of getting pregnant and some are even told to move on to do donor eggs. Let’s address these questions Very simple, I think it’s very easy for the numbers to talk. So first of all, let me make it clear to you right away. The quality of the egg is mainly determined by your age, not by the ability to to make more or less eggs. And not determined by your Anti-Mullerian Hormone (AMH), or your antral follicle count. If you are 35 years or younger, the probability of each egg you produce should have about 15% chance of giving you a live birth baby. If you are 37 to 39 years old, the probability is 8-10% that each egg can make a live birth baby. If you are 40 to 42 years old, it is really only 3-5% chance your eggs can make a live birth baby, regardless of your ovarian reserve. Number 1: If you make less eggs, you still have a very good chance to make a live birth baby. Number 2: Of course from treatment point of view, we need to modify the protocols. If you don’t make more than 3 eggs you do not need to take a daily injection for 9 to 12 days if you are going through in-vitro fertilization and trying to make 15 eggs. A, it will not happen and B, it is not necessary. You just need a more gentle approach. This is what I want to discuss today: the quality and quantity of the egg is not related. Now here’s some extra information. Based on our last 10 years of clinical experience and research, and also some recent publications from our colleagues, it showed that not only heavy medication to make more eggs is unnecessary, it actually can be counterproductive. It can actually reduce the overall quality of your eggs. So by taking heavy drugs, and you are making huge amount of eggs, let’s say 15 to 20 eggs, the overall quality of your eggs maybe reduced dramatically. So this is what I want to point out. In my next clip, I would like to discuss what will be the best strategic approach for ladies who do not make more than 3 to 4 eggs no matter how much medicine you get, and for ladies who may already failed 2 or 3 IVF cycles . What is the best strategic plan for this group of patients? This will be my next video clip topic. Stay tuned. We can continue this conversation. Bye!